Avestagenome Project® International Pvt. Ltd., a pioneer in genomics and preventive health, has announced a landmark research collaboration with the Longevity India Initiative of the Indian Institute of Science (IISc). This partnership represents a significant step toward unraveling the biological mechanisms of aging and translating them into precision healthcare solutions that extend healthy lifespans.
The collaboration builds upon the vision of Dr. Villoo Morawala-Patell, Founder and CMD of Avesthagen Limited & The Avestagenome Project®, who has long emphasized the role of science in serving society. Her work on decoding the genetic heritage of the Zoroastrian-Parsi community has laid the foundation for understanding human longevity and chronic disease prevention.
We are thrilled to collaborate with Longevity India, IISc in decoding the molecular blueprint of healthy aging,” said Dr. Morawala-Patell. “This partnership reflects the heart of our mission—to turn the power of genomics and systems biology into solutions that improve lives. It is my vision to see science not just as discovery, but as delivery—delivering better health, longer life and affordable care for all. I am proud to be associated with Prof. Deepak Saini, IISc and the Longevity India Project.”
Under the leadership of Prof. Deepak Saini, Longevity India has been advancing research on the pathways of aging and resilience. Together with Avestagenome’s richly annotated Biobank and expertise in multi-omics, the collaboration will design and execute joint research projects that integrate genomics, lipidomics, and epigenetics.
“Through this partnership, we have a unique opportunity to compare the genetic landscape of India's diverse population with the remarkable Zoroastrian-Parsi genome. By leveraging complementary expertise and resources, we aim to reveal how distinct genetic backgrounds influence healthy aging—and use these insights to create tailored strategies for longevity and disease prevention that benefit all communities,” Prof. Saini noted.
Cardiovascular Risk Profiling: Studying cholesterol derivatives (oxysterols) alongside whole-genome sequencing data from the Parsi community to identify genetic variants linked to cardiovascular disease.
Cellular Aging & Mitochondrial Health: Screening natural compounds from Avesthagen’s proprietary libraries to restore mitochondrial function and build resilience against age-related diseases such as Alzheimer’s, Parkinson’s, and diabetes.
By combining academic excellence with translational intent, this partnership will pursue novel biomarker discovery, population-specific diagnostics, AI-enabled risk models, and therapeutic innovation. It also aims to generate peer-reviewed publications, intellectual property, and pilot solutions for clinical use.
This collaboration sets a precedent for how Indian academia and industry can together drive global innovation in healthy aging and precision healthcare.