Yashoda Hospitals, Somajiguda, has successfully treated a 10-month-old male child diagnosed with Congenital Amegakaryocytic Thrombocytopenia (CAMT), a rare inherited bone marrow failure disorder marked by severe thrombocytopenia and a high risk of life-threatening bleeding. The child underwent a haploidentical hematopoietic stem cell transplantation, the only curative treatment available for this condition.
The infant was referred to Yashoda Hospitals following persistent low platelet counts. After comprehensive clinical and laboratory evaluation, CAMT was confirmed. In the absence of a fully matched donor, the child’s father was evaluated and selected as a suitable haploidentical stem cell donor, enabling the transplant to proceed without delay.
During the post-transplant hospitalization, the child experienced an episode of aspiration while feeding, leading to sudden respiratory distress, hypoxia, and bradycardia. He was immediately intubated and managed in the Pediatric Intensive Care Unit with mechanical ventilation for four days. With timely critical care intervention and close monitoring, the child made a steady recovery.
As engraftment was achieved and blood counts improved, ventilatory support was successfully withdrawn. The child is now clinically stable and has achieved independence from platelet transfusions, indicating a successful transplant outcome.
Speaking on the case, Dr. Karanam Ashok Kumar, Consultant – Hematology & Bone Marrow Transplantation, Pediatric Oncology, Yashoda Hospitals, Somajiguda, said,
“Congenital amegakaryocytic thrombocytopenia is a rare but serious condition that can be fatal without timely intervention. Stem cell transplantation offers a definitive cure. This case underscores the importance of early diagnosis, rapid referral, and access to advanced transplant facilities. With coordinated multidisciplinary care, even complex pediatric blood disorders can be successfully treated.”
The successful outcome reflects the collaborative efforts of the Departments of Hematology & Transplantation, Pediatrics, Transfusion Medicine, Critical Care, Nursing, and Hospital Management at Yashoda Hospitals.
This case serves as a powerful reminder that many childhood blood disorders once considered life-threatening are now curable with modern medical advancements, provided early diagnosis and appropriate treatment are ensured.
