In a historic milestone for global medical science, Paras Health Gurugram has successfully performed the world’s first living donor liver transplant combined with simultaneous double heart valve surgery.
The complex, life-saving procedure was carried out on a 55-year-old woman from Kyrgyzstan, Anara M, who had been suffering from end-stage autoimmune liver disease along with severe dysfunction of both the mitral and tricuspid heart valves. After years of repeated hospitalizations, she arrived at Paras Health on February 25, 2025, in critical condition, seeking advanced multidisciplinary care.
A thorough pre-transplant evaluation revealed the need for not just a liver transplant, but also surgical repair of both heart valves — a rare and extremely high-risk combination that had never been performed together in a living donor case.
The landmark procedure was led by a highly specialized team including:
Dr. Vaibhaw Kumar, Director, Institute of Liver Transplant & GI Surgery
Dr. Amit Rastogi, Chairman, Institute of Liver Transplant & GI Surgery
Dr. Sanjay Kumar, Vice Chairman, Cardiac Surgery
With key contributions from Dr. Rajnish Monga, Chairman, Gastroenterology & Hepatology, and Dr. Amit Bhushan Sharma, Director & Unit Head, Cardiology.
“It is the first time a living donor liver transplant has been combined with simultaneous mitral and tricuspid valve surgery,” said Dr. Vaibhaw Kumar. “Executing both procedures in one surgical session significantly raised the level of complexity, but it also underscores the depth of expertise, coordination, and technology available at our centre.”
Dr. Sanjay Kumar added, “This was one of the most challenging cases we have encountered. The patient’s heart had to be stabilized first. Only after successfully replacing the mitral valve and repairing the tricuspid valve could the liver transplant proceed safely. This integrated approach saved her life.”
The groundbreaking surgery was performed on March 26, 2025. It began with a 4-hour cardiac procedure to address the heart valves. Following a brief awakening to assess cardiac stability, the team proceeded with a 12-hour living donor liver transplant — resulting in a total operative time of 16 hours. The surgery involved a multidisciplinary team of 18–20 experts including surgeons, anesthesiologists, intensivists, and support staff.
The donor — Anara’s 23-year-old nephew — recovered well and was discharged by day five post-surgery. He returned to Kyrgyzstan within three weeks and has since resumed his normal life, underscoring the safety and success of living donor transplant programs when performed in high-quality centers.
Anara spent 8 days in intensive care and another 7 days in a general ward. She was discharged on the 15th day and returned to her home country after six weeks. Now, three months post-surgery, she is living a fully normal and healthy life.
This extraordinary achievement was supported by Paras Health’s cutting-edge infrastructure, including hybrid operating rooms, AI-assisted surgical planning tools, real-time 3D imaging, and a dedicated transplant ICU.
The hospital plans to publish this case in a leading international medical journal to guide other centers in managing similarly complex multi-organ transplant cases.
This success not only marks a medical breakthrough but also reinforces India’s growing leadership in advanced, high-precision healthcare.